Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives
- authored by
- Torsten Busch, Gerald Dräger, Eike Kunst, Hannah Benson, Florenz Sasse, Karsten Siems, Andreas Kirschning
- Abstract
The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines.
- Organisation(s)
-
Institute of Organic Chemistry
Centre of Biomolecular Drug Research (BMWZ)
- External Organisation(s)
-
Helmholtz Centre for Infection Research (HZI)
AnalytiCon Discovery GmbH, Potsdam
- Type
- Article
- Journal
- Organic and Biomolecular Chemistry
- Volume
- 14
- Pages
- 9040-9045
- No. of pages
- 6
- ISSN
- 1477-0520
- Publication date
- 2016
- Publication status
- Published
- Peer reviewed
- Yes
- ASJC Scopus subject areas
- Biochemistry, Physical and Theoretical Chemistry, Organic Chemistry
- Sustainable Development Goals
- SDG 3 - Good Health and Well-being
- Electronic version(s)
-
https://doi.org/10.1039/c6ob01697a (Access:
Unknown)