Boundedness enforced by mildly saturated conversion in a chemotaxis-May–Nowak model for virus infection

authored by
Mario Fuest
Abstract

We study the system (⋆){u

t=Δu−∇⋅(u∇v)−u−f(u)w+κ,v

t=Δv−v+f(u)w,w

t=Δw−w+v, which models the virus dynamics in an early stage of an HIV infection, in a smooth, bounded domain Ω⊂R

n,n∈N, for a parameter κ≥0 and a given function f∈C

1([0,∞)) satisfying f≥0, f(0)=0 and f(s)≤K

fs

α for all s≥1, some K

f>0 and α∈R. We prove that whenever α<[Formula presented], solutions to (⋆) exist globally and are bounded. The proof mainly relies on smoothing estimates for the Neumann heat semigroup and (in the case α>1) on a functional inequality. Furthermore, we provide some indication why the exponent [Formula presented] could be essentially optimal.

External Organisation(s)
Paderborn University
Type
Article
Journal
Journal of Mathematical Analysis and Applications
Volume
472
Pages
1729-1740
No. of pages
12
ISSN
0022-247X
Publication date
04.2019
Publication status
Published
Peer reviewed
Yes
ASJC Scopus subject areas
Analysis, Applied Mathematics
Sustainable Development Goals
SDG 3 - Good Health and Well-being
Electronic version(s)
https://doi.org/10.1016/j.jmaa.2018.12.020 (Access: Open)