The control of the consumer risk in the Ames assay
- authored by
- Markus Neuhäuser, Ludwig A. Hothorn
- Abstract
Preclinical tests in genetic toxicology represent safety studies. Therefore, the primary concern in the evaluation of Ames test data is the control of the consumer risk, that is, the risk of erroneously concluding safety. Hence, an equivalence test procedure is adequate. This approach is presented beside the two-fold rule and classical tests for differences with respect to an order restricted alternative.
- Organisation(s)
-
Department of Biostatistics
- External Organisation(s)
-
SOLVAY GmbH
- Type
- Article
- Journal
- Drug Information Journal
- Volume
- 31
- Pages
- 363-367
- No. of pages
- 5
- ISSN
- 0092-8615
- Publication date
- 30.12.1997
- Publication status
- Published
- Peer reviewed
- Yes
- ASJC Scopus subject areas
- Pharmacology (nursing), Drug guides, Public Health, Environmental and Occupational Health, Pharmacology (medical)
- Sustainable Development Goals
- SDG 3 - Good Health and Well-being
- Electronic version(s)
-
https://doi.org/10.1177/009286159703100207 (Access:
Closed)
https://doi.org/10.15488/3052 (Access: Open)
