The control of the consumer risk in the Ames assay

authored by
Markus Neuhäuser, Ludwig A. Hothorn
Abstract

Preclinical tests in genetic toxicology represent safety studies. Therefore, the primary concern in the evaluation of Ames test data is the control of the consumer risk, that is, the risk of erroneously concluding safety. Hence, an equivalence test procedure is adequate. This approach is presented beside the two-fold rule and classical tests for differences with respect to an order restricted alternative.

Organisation(s)
Department of Biostatistics
External Organisation(s)
SOLVAY GmbH
Type
Article
Journal
Drug Information Journal
Volume
31
Pages
363-367
No. of pages
5
ISSN
0092-8615
Publication date
30.12.1997
Publication status
Published
Peer reviewed
Yes
ASJC Scopus subject areas
Pharmacology (nursing), Drug guides, Public Health, Environmental and Occupational Health, Pharmacology (medical)
Sustainable Development Goals
SDG 3 - Good Health and Well-being
Electronic version(s)
https://doi.org/10.1177/009286159703100207 (Access: Closed)
https://doi.org/10.15488/3052 (Access: Open)