Sequential and Multiple Testing for Dose-Response Analysis
- authored by
- Walter Lehmacher, Meinhard Kieser, Ludwig Hothorn
- Abstract
For the analysis of dose-response relationship under the assumption of ordered alternatives several global trend tests are available. Furthermore, there are multiple test procedures which can identify doses as effective or even as minimally effective. In this paper it is shown that the principles of multiple comparisons and interim analyses can be combined inflexible and adaptive strategies for dose-response analyses; these procedures control the experimentwise error rate.
- Organisation(s)
-
Department of Biostatistics
- External Organisation(s)
-
University of Cologne
Ingenieurbüro Lohmeyer GmbH and Co. KG
- Type
- Article
- Journal
- Therapeutic Innovation & Regulatory Science
- Volume
- 34
- Pages
- 591-597
- No. of pages
- 7
- ISSN
- 2168-4790
- Publication date
- 30.12.2000
- Publication status
- Published
- Peer reviewed
- Yes
- ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Public Health, Environmental and Occupational Health, Pharmacology (medical)
- Sustainable Development Goals
- SDG 3 - Good Health and Well-being
- Electronic version(s)
-
https://doi.org/10.1177/009286150003400227 (Access:
Closed)
https://doi.org/10.15488/3045 (Access: Open)
