Economic evaluation of human papillomavirus screening in Germany

verfasst von
T. Mittendorf, K. U. Petry, T. Iftner, W. Greiner, J. M. Von der Schulenburg
Abstract

Cytology-based screening programs for cervical cancer have been effective in reducing cancer incidence and preventing premature deaths worldwide. However, there is concern about the relatively low sensitivity of current screening procedures. Although the causal association between infection with certain high-risk types of human papilloma virus (HPV) and the development of cervical cancer has been clearly established, testing for the major risk factor is not part of current screening practice. We created a tree decision model over time to evaluate different policy choices for implementing a population-based screening program. Results of the economic analysis indicate that testing with any implemented HPV DNA testing (stand alone or in combination with the Papanicolaou smear) is superior to cytology and measures presently in use. Additional costs per life-years gained cannot be reported because the HPV branches had fewer discounted overall costs (€222 million vs. €82 and €76 million, respectively), and they saved more life years (19,599 vs. 19,163 and 903, respectively) then the smear alternative. Any HPV DNA testing is preferable over the current state of the art performed in Germany. This is true not only for economic reasons but also for life-years gained. Therefore HPV DNA testing must become an essential component to back up the relatively weak sensitivity of the standard procedure.

Organisationseinheit(en)
Center for Health Economics Research Hannover (CHERH)
Externe Organisation(en)
Eberhard Karls Universität Tübingen
Typ
Artikel
Journal
European Journal of Health Economics
Band
4
Seiten
209-215
Anzahl der Seiten
7
ISSN
1618-7598
Publikationsdatum
09.2003
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
ASJC Scopus Sachgebiete
Volkswirtschaftslehre, Ökonometrie und Finanzen (sonstige), Health policy
Ziele für nachhaltige Entwicklung
SDG 3 – Gute Gesundheit und Wohlergehen
Elektronische Version(en)
https://doi.org/10.1007/s10198-003-0187-0 (Zugang: Geschlossen)