An overview on the mechanisms of encapsulation of polyphenols used to help fight diabetes mellitus

verfasst von

Stephen Adeniyi Adefegha, Patricia Oyeronke Ogundare, Ganiyu Oboh, Tuba Esatbeyoglu, Jutta Papenbrock

Abstract

Diabetes mellitus (DM) represents a condition of deadly physiological condition characterized by a rate that has increased significantly in the past couple of decades. As the condition's incidence and severity increase, many medicinal techniques are being explored as potential solutions. Among is dietary polyphenols that was documented for their efficacy in addressing diabetes and related conditions such as cardio-respiratory implications, for various treatment endpoints. However, these biological properties of polyphenol are faced with challenges; this includes their instantaneous removal, a lack of water solubility, volatility at a low pH value, and sized particles which can affect its bioavailability and effectiveness. In order to overcome this challenge, nanotechnology (nanoencapsulation) which represents a fascinating niche for investigative work is then applied in order to further improve the diagnostic and therapeutic value of this compound (polyphenol). This current article aims to discuss the several research results that have been done and reported on the nanoencapsulation polyphenols' approach in the onset of type 2 diabetes.

Organisationseinheit(en)

Institut für Lebensmittelwissenschaft und Humanernährung
Institute of Food and One Health
Molekulare Lebensmittelchemie und -entwicklung
Institut für Botanik

Externe Organisation(en)

Federal University of Technology, Akure

Typ

Übersichtsarbeit

Journal

Discover Food

Band

5

Anzahl der Seiten

26

ISSN

2731-4286

Publikationsdatum

09.06.2025

Publikationsstatus

Veröffentlicht

Peer-reviewed

Ja

ASJC Scopus Sachgebiete

Agrar- und Biowissenschaften (sonstige), Agronomie und Nutzpflanzenwissenschaften, Aquatische Wissenschaften, Biochemie, Genetik und Molekularbiologie (sonstige)

Ziele für nachhaltige Entwicklung

SDG 3 – Gute Gesundheit und Wohlergehen

Elektronische Version(en)

https://doi.org/10.1007/s44187-025-00455-x (Zugang: Offen)